No, the speakers will not work if the fuse is blown. It almost sounds like your rear speakers are not working. The rears are the ones that give the most bass, but the fronts do give off a considerable amount. So if the rears are not working, it would pretty much sound like your problem. This is probably a dumb question, but is the fader and the balance set right? According to my owners manual the Bose fuse is in the trunk. On the left side, there is a small panel with little mini fuses and the bose fuse is there. Try turning the radio on and listen in the back seat to see if your rear speakers are working.