Here are the simple instructions on how to use your navigation system while the car is in drive:

1. With the GPS already in map mode, select the ROUTE button.

2. At this point if you are in motion, only the “ROUTE PREFERENCES” option will be available. Now hold your finger in lower-right corner of the screen for about 8 seconds. There is a hidden button there.

3. You will hear a beep and be presented with a menu that has ten options. Select the RUN button, it will remain highlighted. I don’t know if this is a defect just on my unit or they are all like this, but my “RETURN” button is partially underneath the clock. It is very tricky, but if you slide your finger upward while pressing the screen, you can select the RETURN button. This may take some practice if your system is the same as mine.
Warning: Don’t mess around with any option unless you know what you’re doing.
You have been warned! 
4. At this point you should see
all the navigation options while the car is in motion. Your
passenger can now input an address or POI while you’re driving and keeping your eyes on the road ;- )
You don't need to be in motion to unlock the hidden options but you
will have to repeat these steps each time you start the car.
Dislclaimer: I am not responsible for YOUR actions. 