I'd say the odds of the manual being an option are pretty good, given the new parts bin 7-speed Tremec manual they have now in the C7 Vette. It gives them the option to play the MPG card with that tall 7th gear.
I think if they want to follow the current model where the V1 was, "holy crap, a fast Caddy", V2 was, "556hp, Nurburgring record, OMG!!!", to keep in line with their shock and awe that is the CTS-V they need to keep pushing the envelope, i.e., 700hp, lighter than the base CTS, and sub 3 sec 0-60 via an AWD tranny, all while keeping MSRP below $80k. Won't happen but it should! And they should do another wagon, they only had to sell like 7 to turn a profit on the V2 wagon experiment which I think they did.
Automobile(s): 2012 V sedan crystal red/ light titanium A6, 2010 GS LPE 650
Re: Thoughts on CTS V3
It's hard to tell at this point what will power the V3. As others have said, could be a supercharged LT1( LT4 ?), a twin turbo V8, etc. Seems likely they'll have an 8 speed auto that will also be used in the corvette. As to having a wagon, I guess it depends on the business case that can be made. Chrysler stopped making their similar wagons over time. Although the CTS-V wagon is certainly very practical & some love the looks, many can't get over the " station wagon " look & to put it bluntly think it looks goofy & not cool, whereas the sedan has the " look". The coupe is more of a love it or hate it look, with more loving the look than hating it. Imho, I love the looks of the sedan( which I have), love the practicality of the wagon, & the although I like the looks of the coupe, it's daily driver practicality limitations weigh against it. I think GM is weighing those factors & others, as they plan their V3 offerings.